What is CBG? Guide to cannabigerol with CBGenius

Man running with sunrise in the background

CBG is sometimes referred to as the “stem cell” of cannabinoids, and that’s a slightly misleading moniker. Cannabigerol is also called the “Rolls Royce” of cannabis, and we certainly don’t refute that claim.

We don’t sell cannabigerol products at CBGenius.net (yet), but “CBG” is still in our name. It’s high time we provided the definitive word on CBG and explained what all the fuss is about regarding this elusive but increasingly popular cannabis constituent.

What is CBG oil?

Is the “CBG stem cell” myth or fact? While it’s true that cannabigerol bears a relationship to other cannabinoids similar to that which stem cells have with the other cells in our bodies, not every single cannabinoid comes from CBG. Rather, cannabigerol is used to make some of the most popular cannabinoids as Cannabis sativa flowers and matures, which has led to this cannabis constituent’s thrust-upon role as the cannabinoid stem cell.

More than 100 cannabinoids have been discovered to date, and among them, CBG shows some of the most promise. Until recently, CBG commerce has been limited since this cannabinoid isn’t very abundant in cannabis. Certain breeders are now starting to cultivate CBG hemp, however, which means that the era of cheap cannabigerol products is right over the horizon.

The current status of the CBG industry

If you’re looking for CBG hemp or CBG flower right now, you might be disappointed. Great headway has certainly been made in the process of breeding CBG-rich cannabis strains, but most of these phenotypes still aren’t available to the public.

The average hemp strain has about 1% CBG, so existing cannabigerol companies have to waste incredible amounts of biomass to make their products. While this impediment has traditionally been seen as an insurmountable wall, everyone seems to conveniently forget that cannabis strains with 20% cannabidiol would have seemed like science fiction two decades ago.

Hemp evolves as fast as we can breed it, and before long, we’ll have cannabis “super-strains” with perfectly-balanced profiles of CBD, CBN, THCV, CBG, and all the other beneficial, non-intoxicating cannabinoids. It’s only a matter of time.

Is it possible to make CBG isolate?

Certain Cannabis sativa phenotypes are naturally high in CBG, and scientists still aren’t entirely sure what causes this genetic variance. Just as it’s possible to isolate THC or CBD molecules present in cannabis, it’s also possible to isolate pure cannabigerol.

In fact, it’s now even possible to molecularly reconstruct cannabinoids out of terpenes, which are special oils also present in cannabis. At this stage, full-scale deployment of these semi-synthetic cannabinoids hasn’t occurred, but it will soon be possible to make any cannabinoid in a lab without having to worry about breeding cannabinoid-rich cannabis phenotypes.

Isolate CBD, THC, and CBG are about to be outdated, and people will turn to hemp oil as the natural alternative to semi-synthetic, reconstructed-terpene cannabinoids, which will soon be everywhere. That’s why focusing on making our CBD products organic and non-GMO makes the most long-term sense; within a few short years, natural hemp oil will be seen as an even more boutique item as new technologies disrupt the industry once again.

Artist’s rendition of DNA double helix
It looks like CBG affects our bodies in some pretty profound ways

CBG oil benefits

Since CBG is a cannabis constituent, we’re reluctant to dive into too much detail when it comes to the potential benefits of cannabigerol. While this cannabinoid isn’t under the strict surveillance that’s applied to CBD and THC, it’s likely that CBG will one day be subject to the same regulatory measures that are currently descending on the recreational pot and CBD industries.

We don’t offer any products that are high in CBG here at CBGenius.net at this point, so we’ll go out on a limb slightly by linking to some of the studies that have been done so far on CBG and its potential medical benefits:

  1. In Vitro Model of Neuroinflammation: Efficacy of Cannabigerol, a Non-Psychoactive Cannabinoid
  2. Evidence that the plant cannabinoid cannabigerol is a highly potent α2-adrenoceptor agonist and moderately potent 5HT1A receptor antagonist
  3. A Cannabigerol Derivative Suppresses Immune Responses and Protects Mice from Experimental Autoimmune Encephalomyelitis
  4. Cannabigerol Action at Cannabinoid CB1 and CB2 Receptors and at CB1–CB2 Heteroreceptor Complexes

Most researchers agree that the CBG benefits that are the most impressive are increased anandamide or “bliss molecule” levels, increased GABA levels, and a potent antibacterial profile. There’s no doubt that there are cheaper ingredients out there that work better as antibacterials. At the same time, no other cannabinoids have been demonstrated to have the antibacterial profile that CBG appears to possess, which alone makes this cannabinoid worthy of further notice.


The benefits of CBG and CBD overlap in many ways, but these cannabinoids are also very different. While CBD has tons of other strong points, for instance, this cannabis constituent doesn’t appear to display any significant antibacterial properties, which means that CBG can fill in cannabidiol’s gaps.

While CBD and CBG might have similar effects as observed by human subjects, these two substances have different mechanisms of action. As I’ve covered in previous articles, CBD appears to primarily exert its effects by influencing the TRPV1 and 5-HT1A systems in the body, but CBG primarily interacts with anandamide and GABA instead.

Cannabinoids work best when they work together

It’s not that either CBD or CBG are weak on their own, but they work so much better when they are together. Traditionally, cannabis was THC-rich, and all the other members of the cannabinoid family were shunted to the side.

Cannabidiol has finally risen to its rightful place in the cannabis constituent hierarchy, and the success of this cannabinoid is uplifting all its comrades along with it. CBG has so much to offer, and now that people are becoming increasingly aware of all the cannabinoids beyond THC, it’s only a matter of time until CBG also finds its voice.

Cannabis consumption of the future

In decades to come, we’ll look back at our current cannabinoid consumption methods and laugh. As a culture, we’re just now moving away from smoking and embracing vaping, and for the most part, we’re stuck with Cannabis sativa products that are high in one or both of the two lone cannabinoids, THC and CBD, that we’ve succeeded somewhat in bringing into the fold.

The people of the future will use nanotechnology to disperse exact ratios of cannabis constituents evenly throughout their bodies at set intervals. Each cannabinoid will be equally accessible, and it’s even possible that Cannabis sativa itself will continue to evolve and bear more unique fruit.

It’s now time to start looking forward and embracing the ways that cannabinoid culture is about to change. The days of the unquestioned tyranny of THC are officially over, and the fringe cannabinoid uprising is fully underway.

Hemp field with mountains in background
Will the other cannabis constituents ever see the light of day?

What about the other cannabinoids?

Each member of the cannabinoid family has its own tale to tell, and embracing CBG is only the beginning of how people will start to enjoy cannabis and natural health in coming years. Once classified a contraband substance, cannabis is gradually taking its deserved place within the contemporary pharmacopeia, and I’m sure we’ll explore the virtues of each cannabinoid in detail as cannabis policy and public opinion continue to evolve.

For now, we’ll continue to focus on CBD and help this cannabinoid gain a secure foothold within American and global society. Once cannabidiol has become completely normalized, it will be easy to help all the other cannabinoids gain the respect they deserve, and expect the various constituents of the cannabis plant to become even more popular as technology and natural health deliver the keys to longevity and prosperity for which we have always strived.

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CBG for sale from CBGenius

At CBGenius, we focus on parting from the ways of the past and embracing the innovations of the future. Such a mindset has always been at the core of the spirit of science, and we fully believe that honest scientific inquiry will eventually award all the cannabinoids their due diligence and deserved rewards.

Offering CBG products is still off the menu for us at the time being. Right now, sourcing hemp with high levels of CBG is practically impossible, and we aren’t ready to rely on non-hemp sources of this cannabinoid.

It’s sobering to think about, but remember that everyone who currently makes CBG products wastes an incredible amount of hemp in the process. Each hemp plant that yields less than 1% CBG absorbed just as many nutrients and dollars as a plant with 20% CBD, which seems unfair.

As human beings, we have always used our ingenuity and technology to right the injustices of the world, and we’ll surely do the same when it comes to CBG production. It’s only a matter of time until intrepid cannabis breeders succeed in doing exactly the same thing they did with CBD. All it takes is the time and diligence required to selectively breed cannabis phenotypes with high concentrations of CBG until you land on a strain that bears the desired characteristics.

The moment that it becomes ethical and logistically feasible to offer CBG-rich hemp products, you’ll know where to go. CBGenius is the world’s finest purveyor of Colorado-grown, organic CBD products, and we always provide you with more CBD, customer service, and education than anybody else for far less. Whenever you have cannabinoid questions you need answered or it’s time to stock up on natural CBD oil, always rely on the cannabis PhDs at CBGenius.

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